Janice Schwartz, MD

1990 - Geriatrics, UCLA
1981 - Cardiology, Stanford University
1978 - Cardiology, Cedar Sinai Medical Center
1977 - Internal Medicine, Cedar-Sinai Medical Center
1975 - Internal Medicine, LACounty/USC
MD, 1974 - Medicine, Tulane University, School of Medicine
1970 - Biology, Newcomb College
Honors and Awards
  • Award of Excellence in Clinical Pharmacology, PhRMA, 2019
  • William Abrams Award in Geriatric Clinical Pharmacology, American Society of Clinical Pharmacology and Therapeutics, 2012
  1. Schwartz JB, Liu RY, Boscardin J, Liu Q, Lau SWJ, Khatri S, Tarn D. Attitudes on participation in clinical drug trials: A nationally representative survey of older adults with multimorbidity. 2024. PMID: 38485469

  2. Lau SWJ, Huang Y, Hsieh J, Wang S, Liu Q, Slattum PW, Schwartz JB, Huang SM, Temple R. Participation of Older Adults in Clinical Trials for New Drug Applications and Biologics License Applications From 2010 Through 2019. 2022. PMID: 36239939

  3. Sukumar S, Orkaby AR, Schwartz JB, Marcum Z, Januzzi JL, Vaduganathan M, Warraich HJ. Polypharmacy in Older Heart Failure Patients: a Multidisciplinary Approach. 2022. PMID: 35723783

  4. Thomas A, Fang MC, Kogan S, Hubbard CC, Friedman PN, Gong L, Klein, TE, Nutescu, EA, O’Brien, TJ, Tuck M, Perera M.A., Schwartz, JB. Apixaban Concentrations in Routine Clinical Care of Older Adults with Non-valvular Atrial Fibrillation 2022. PMID:

  5. Thomas A, Fang MC, Kogan S, Hubbard CC, Friedman PN, Gong L, Klein TE, Nutescu EA, O'Brien TJ, Tuck M, Perera MA, Schwartz JB. Apixaban Concentrations in Routine Clinical Care of Older Adults With Nonvalvular Atrial Fibrillation. 2022. PMID: 37961076

  6. Liu Q, Schwartz JB, Slattum PW, Lau SWJ, Guinn D, Madabushi R, Burckart G, Califf R, Cerreta F, Cho C, Cook J, Gamerman J, Goldsmith P, van der Graaf PH, Gurwitz JH, Haertter S, Hilmer S, Huang SM, Inouye SK, Kanapuru B, Pirmohamed M, Posner P, Radziszewska B, Talbot HK, Temple R. Roadmap To 2030 For Drug Evaluation In Older Adults. 2021. PMID: 34656074

  7. Schwartz JB, Kogan SC, Fang MC. Preventing Bleeding With Direct-Acting Oral Anticoagulants. 2021. PMID: 34649705

  8. Hilmer SN, Petrovic M, Le Couteur DG, Schwartz JB, Thuermann P. Development, evaluation and use of COVID-19 vaccines in older adults: Preliminary principles for the pandemic and beyond. 2021. PMID: 34342013

  9. Sukumar S, Cabero M, Tiu S, Fang MC, Kogan SC, Schwartz JB. Anti-factor Xa activity assays of direct-acting oral anticoagulants during clinical care: An observational study. 2021. PMID: 34013157

  10. Tarn DM, Barrientos M, Pletcher MJ, Cox K, Turner J, Fernandez A, Schwartz JB. Perceptions of Patients with Primary Nonadherence to Statin Medications. 2021. PMID: 33452090

  11. Tarn DM, Schwartz JB. Polypharmacy: A Five-Step Call to Action for Family Physicians. 2020. PMID: 33151528

  12. Tarn DM, Barrientos M, Wang AY, Ramaprasad A, Fang MC, Schwartz JB. Prevalence and Knowledge of Potential Interactions Between Over-the-Counter Products and Apixaban. 2019. PMID: 31658372

  13. Sukumar S, Gulilat M, Linton B, Gryn SE, Dresser GK, Alfonsi JE, Schwarz UI, Kim RB, Schwartz JB. Apixaban Concentrations with Lower than Recommended Dosing in Older Adults with Atrial Fibrillation. 2019. PMID: 31112620

  14. Schwartz JB, Schmader KE, Hanlon JT, Abernethy DR, Gray S, Dunbar-Jacob J, Holmes HM, Murray MD, Roberts R, Joyner M, Peterson J, Lindeman D, Tai-Seale M, Downey L, Rich MW. Pharmacotherapy in Older Adults with Cardiovascular Disease: Report from an American College of Cardiology, American Geriatrics Society, and National Institute on Aging Workshop. 2018. PMID: 30536694

  15. Schwartz JB, Gallagher JC, Jorde R, Berg V, Walsh J, Eastell R, Evans AL, Bowles S, Naylor KE, Jones KS, Schoenmakers I, Holick M, Orwoll E, Nielson C, Kaufmann M, Jones G, Bouillon R, Lai J, Verotta D, Bikle D. Determination of Free 25(OH)D Concentrations and Their Relationships to Total 25(OH)D in Multiple Clinical Populations. 2018. PMID: 29955795

  16. Goetzl EJ, Nogueras-Ortiz C, Mustapic M, Mullins RJ, Abner EL, Schwartz JB, Kapogiannis D. Deficient neurotrophic factors of CSPG4-type neural cell exosomes in Alzheimer disease. 2018. PMID: 29924942

  17. Moore KL, Patel K, Boscardin WJ, Steinman MA, Ritchie C, Schwartz JB. Medication burden attributable to chronic co-morbid conditions in the very old and vulnerable. 2018. PMID: 29684077

  18. Goetzl EJ, Schwartz JB, Abner EL, Jicha GA, Kapogiannis D. High complement levels in astrocyte-derived exosomes of Alzheimer disease. 2018. PMID: 29406582

  19. Schwartz J, Merrill S, de Leon N, Thompson A, Fang M. Dosing Accuracy of Direct Oral Anticoagulants in an Academic Medical Center. 2017. PMID: 28699943

  20. Goetzl EJ, Schwartz JB, Mustapic M, Lobach IV, Daneman R, Abner EL, Jicha GA. Altered cargo proteins of human plasma endothelial cell-derived exosomes in atherosclerotic cerebrovascular disease. 2017. PMID: 28476896

  21. Schwartz JB. Dabigatran Compared With Rivaroxaban vs Warfarin. 2017. PMID: 28460097

  22. Ahmed GF, Bathena SP, Brundage RC, Leppik IE, Conway JM, Schwartz JB, Birnbaum AK. Pharmacokinetics and Saturable Absorption of Gabapentin in Nursing Home Elderly Patients. 2017. PMID: 28070716

  23. Goetzl EJ, Kapogiannis D, Schwartz JB, Lobach IV, Goetzl L, Abner EL, Jicha GA, Karydas AM, Boxer A, Miller BL. Decreased synaptic proteins in neuronal exosomes of frontotemporal dementia and Alzheimer's disease. 2016. PMID: 27601437

  24. Goetzl EJ, Mustapic M, Kapogiannis D, Eitan E, Lobach IV, Goetzl L, Schwartz JB, Miller BL. Cargo proteins of plasma astrocyte-derived exosomes in Alzheimer's disease. 2016. PMID: 27511944

  25. Goetzl EJ, Boxer A, Schwartz JB, Abner EL, Petersen RC, Miller BL, Kapogiannis D. Altered lysosomal proteins in neural-derived plasma exosomes in preclinical Alzheimer disease. 2015. PMID: 26062630

  26. Goetzl EJ, Boxer A, Schwartz JB, Abner EL, Petersen RC, Miller BL, Carlson OD, Mustapic M, Kapogiannis D. Low neural exosomal levels of cellular survival factors in Alzheimer's disease. 2015. PMID: 26273689

  27. Dai X, Hummel SL, Salazar JB, Taffet GE, Zieman S, Schwartz JB. Cardiovascular physiology in the older adults. 2015. PMID: 26089840

  28. Lai JC, Bikle DD, Lizaola B, Hayssen H, Terrault NA, Schwartz JB. Total 25(OH) vitamin D, free 25(OH) vitamin D and markers of bone turnover in cirrhotics with and without synthetic dysfunction. 2015. PMID: 25757956

  29. Kapogiannis D, Boxer A, Schwartz JB, Abner EL, Biragyn A, Masharani U, Frassetto L, Petersen RC, Miller BL, Goetzl EJ. Dysfunctionally phosphorylated type 1 insulin receptor substrate in neural-derived blood exosomes of preclinical Alzheimer's disease. 2014. PMID: 25342129

  30. Fiandaca MS, Kapogiannis D, Mapstone M, Boxer A, Eitan E, Schwartz JB, Abner EL, Petersen RC, Federoff HJ, Miller BL, Goetzl EJ. Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: A case-control study. 2014. PMID: 25130657

  31. Steinman MA, Miao Y, Boscardin WJ, Komaiko KD, Schwartz JB. Prescribing quality in older veterans: a multifocal approach. 2014. PMID: 25002159

  32. Schwartz JB, Moore KL, Yin M, Sharma A, Merenstein D, Islam T, Golub ET, Tien PC, Adeyemi OM. Relationship of vitamin D, HIV, HIV treatment, and lipid levels in the Women's Interagency HIV Study of HIV-infected and uninfected women in the United States. 2014. PMID: 24668135

  33. Schwartz JB, Lai J, Lizaola B, Kane L, Weyland P, Terrault NA, Stotland N, Bikle D. Variability in free 25(OH) vitamin D levels in clinical populations. 2013. PMID: 24240067

  34. Mitsuhashi M, Taub DD, Kapogiannis D, Eitan E, Zukley L, Mattson MP, Ferrucci L, Schwartz JB, Goetzl EJ. Aging enhances release of exosomal cytokine mRNAs by Aß1-42-stimulated macrophages. 2013. PMID: 24014820

  35. Steinman MA, Lee SJ, John Boscardin W, Miao Y, Fung KZ, Moore KL, Schwartz JB. Patterns of multimorbidity in elderly veterans. Volume 60 of Issue 10. 2012. PMID: 23035702

  36. Taub DD, Hesdorffer CS, Ferrucci L, Madara K, Schwartz JB, Goetzl EJ. Distinct energy requirements for human memory CD4 T-cell homeostatic functions. 2012. PMID: 22972918

  37. Moore KL, Boscardin WJ, Steinman MA, Schwartz JB. Age and sex variation in prevalence of chronic medical conditions in older residents of U.S. nursing homes. 2012. PMID: 22463062

  38. Hesdorffer CS, Malchinkhuu E, Biragyn A, Mabrouk OS, Kennedy RT, Madara K, Taub DD, Longo DL, Schwartz JB, Ferrucci L, Goetzl EJ. Distinctive immunoregulatory effects of adenosine on T cells of older humans. 2011. PMID: 22121051

  39. Schwartz JB, Volterrani M, Caminiti G, Marazzi G, Fini M, Rosano GM, Iellamo F. Effects of testosterone on the Q-T interval in older men and older women with chronic heart failure. 2011. PMID: 21615419

  40. Huang MC, Greig NH, Luo W, Tweedie D, Schwartz JB, Longo DL, Ferrucci L, Ershler WB, Goetzl EJ. Preferential enhancement of older human T cell cytokine generation, chemotaxis, proliferation and survival by lenalidomide. 2010. PMID: 21130040

  41. Goetzl EJ, Huang MC, Kon J, Patel K, Schwartz JB, Fast K, Ferrucci L, Madara K, Taub DD, Longo DL. Gender specificity of altered human immune cytokine profiles in aging. 2010. PMID: 20453111

  42. Schwartz JB and Abernethy, DR. 2009; 85 (1): 3-10.. Clin Pharmacol Ther 2009. PMID:

  43. Verotta D, Schwartz JB.. Clin Pharmacol Ther 2009. PMID:

  44. Kang D, Schwartz JB, Verotta D. Sample size computations for PK/PD population models. 2005. PMID: 16284914

  45. Kadish AH, Greenland P, Limacher MC, Frishman WH, Daugherty SA, Schwartz JB. Estrogen and progestin use and the QT interval in postmenopausal women. 2004. PMID: 15485516

  46. Schwartz JB. Sudden cardiac death among women in the United States. 2003. PMID: 14638535

  47. Kang D, Verotta D, Krecic-Shepard ME, Modi NB, Gupta SK, Schwartz JB. Population analyses of sustained-release verapamil in patients: effects of sex, race, and smoking. 2003. PMID: 12545141

  48. Schwartz JB. The influence of sex on pharmacokinetics. 2003. PMID: 12537512

  49. Haller C, Schwartz JB. Pharmacologic agents for weight reduction. 2002. PMID: 12380196

  50. Schwartz JB. Peripheral arterial disease: drug therapy. 2002. PMID: 12192882

  51. Schwartz JB. Pharmacogenetics: has it reached the clinic? 2002. PMID: 11974670

  52. Schwartz JB. Anticoagulant and thrombolytic therapies in women. 2002. PMID: 11859682